The analysis approach described here can be a template for future studies aimed at understanding TCR repertoires where epitope and/or HLA genotype information is unknown and has the potential to define antigen-specific repertoire features that could be used as biomarkers of disease. repertoire ( plural repertoires ) A list of dramas, operas, pieces, parts, etc., which a company or a person has rehearsed and is prepared to perform or display. The possibilities are endless: Throw a ball, make dinner, ride a bike, raise your hand, scratch. Using bulk Teff and Treg data from 9 of the 27 individuals in this study, we discovered 253 Teff- and 74 Treg-exclusive neighborhoods, suggesting differences in antigen-recognition across the phenotypic compartments. Behavior repertoire refers to all the behaviors a person can do. This network was broken into 990 distinct neighborhoods that were individually probed for their tendency to represent Teff or Treg sequences. From Longman Dictionary of Contemporary English Related topics: Performing repertoire /reptw -prtwr/ noun countable usually singular 1 all the plays, pieces of music etc that a performer or group knows and can perform in somebody’s repertoire The group include some techno in their repertoire. Given peanut is a polyantigenic stimulant, we illustrated the local homology of the psCDR3s with a network analysis that clustered sequences based on the presence of either an enriched motif, a low Levenshtein distance (distance = 1), or evidence of convergent recombination as defined by multiple nucleotide rearrangements that corresponded to the same amino acid sequence. Motif analysis revealed 149 unique motifs that were both highly enriched and public within the psCDR3s. The first known use of the word repertoire was in 1847. 2 Musicians often have a musical repertoire. Psychology definition for Behavioral Repertoire in normal everyday language, edited by psychologists, professors and leading students. Because the details on the modalities, locations and sensations associated with the symptoms may be exhaustive, repertories are typically very large. These putatively-specific sequences displayed enhanced homology and reduced diversity as compared to randomly sampled CDR3βs, which is consistent with independently published antigen-specific populations. A repertoire ( / rprtwr /) 1 is a list or set of dramas, operas, musical compositions or roles which a company or person is prepared to perform. A reference book which lists homeopathic symptoms and the remedies used to treat them. In this study, we elucidated 7345 putatively peanut-specific CDR3βs from 27 peanut-allergic individuals by applying a novel statistical approach to an existing TCRβseq data set that consisted of in vitro peanut-activated and memory resting T cell sequences. Peanut-specificity of a T cell is conferred by its TCR and more specifically, the CDR3 of the β-chain. Abstract The induction and persistence of peanut allergies is fundamentally dependent on T cells’ ability to recognize allergenic antigens.
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